Symposium Program Overview 2-7 pm
13:00‐14:00 Registration (hang up posters, copy talks on dedicated speakers PC)
14:00‐14:05 Opening (Franziska Richter Assencio, speaker ZSN board)
14:05‐14:20 Welcome notes by University Presidents (chair: Joachim Krauss, Neurosurgery, MHH)
- 14:05‐14:10 Prof. Dr. Denise Hilfiker‐Kleiner (MHH)
- 14:10‐14:15 Prof. Dr. Klaus Osterrieder (TiHo)
- 14:15‐14:20 Prof. Dr. Hans Jürgen Prömel (HMTMH)
14:20‐ 14:50 Kick‐off talks (chair: Joachim Krauss, Neurosurgery, MHH)
- 14:20‐14:30 Aiden Haghikia (Neurology, MHH)
- 14:30‐14:40 Franziska Richter Assencio (Pharmacology, TiHo)
- 14:40‐14:50 Florian Worschech (IMMM, HMTMH)
14:50‐16:10 Short talks of ZSN members I (chair: Maximilian Lenz, Neuroanatomy, MHH)
- Kerstin Schwabe (Neurosurgery, MHH) Translational aspects of cognitive behavior and neural processing of sensory information using the three‐class oddball paradigm
- Amelie Eichler (Neuroanatomy, MHH) Functional tissue screening reveals synaptic dysfunction in anti‐ DAGLA autoimmune encephalitis
- Bettina Seeger (Toxicology, TiHo) Modeling Infection‐Induced Neurodevelopmental Disorders in a Human Stem Cell–Based Brain Model
- Nadine Brückner (Virology, MHH) Repression and maintenance of Varicella‐zoster virus genomes during quiescent infection
- Johanna Ernst (Neurology, MHH) Biomarker‐Based Identification of Cardioembolic Stroke using Symmetric Dimethylarginine
- Sebastian Meller (Neurology, TiHo) Neuromodulation of the Olfactory System against Epilepsy: Mapping and Decoding Olfactory Pharmacology to Combat Neurological Diseases
- Hauke Thiesler (Clinical Biochemistry, MHH) Intranasal application of polysialic acid fragments of specific size alleviate synaptic and cognitive symptoms in mouse models of dementia
- Maren von Köckritz‐Blickwede (Biochemistry, TiHo) Oxygen‐Dependent Modulation of Neutrophil Responses in Bacterial Meningitis
- Evgeni Ponimaskin (Neurophysiology, MHH) Molecular microscopy for understanding neuronal function and dysfunction
- Frank Brand (Human genetics, MHH) Germline variants in ATM, BRCA2, other cancer predisposition and novel candidate genes are implicated in glioma risk in adult glioma patients with a familial or personal history of tumors
16:10‐17:00 Group photo in the lecture hall, followed by poster session with coffee break
17:00‐18:30 Short talks of ZSN members II (chair: Andreas Beineke, Pathology, TiHo)
11. Peter Claus (Psychiatry, MHH) The neurodevelopmental and neurodegenerative disease Spinal Muscular Atrophy (SMA) as a paradigm for causal analyses of pathomechanisms
12. Jan‐Philipp Machtens (Neurophysiology, MHH) Glutamate transport at atomic resolution
13. Silja Hein (Physiology, TiHo) Effects of feacal supernatants from human irritable bowel syndrom patients on enteric and dorsal root ganglia neurons
14. Fabian Sternkopf (IMMM, HMTMH) Musicians' Pain: Altered Pain Processing in Musicians
15. Ingo Gerhauser (Pathology, TiHo) Enzyme inhibition as treatment strategy in GM1 gangliosidosis
16. Tillmann Krüger (Psychiatry, MHH) Persistent genital arousal disorder/genitopelvic dysesthesia (PGAD/GPD): Investigation of clinical features and brain activity at rest (rsfMRI) in a rare and unknown disease
17. Lisa Maria Haiber (Toxicology, TiHo) Establishing Chemical Labeling of Cell‐Surface Glycans in 3D Human Neurospheres to Study Physiological and Stress‐Induced Remodeling
18. Meike Dirks (Neurology, MHH) ACCESS – Outreach medical care for housebound patients with Post‐ COVID syndrome or ME/ CFS of any cause
19. Herbert Hildebrandt (Clinical Biochemistry, MHH) PolySia‐Siglec interactions as novel innate immune checkpoints in glioblastoma, myelin repair and aging
20. Hanna Felicitas Klein (IMMM, HMTMH) Temporal prediction and accuracy in pianists with task‐ specific dystonia
21. Ulrich Kalinke (TWINCORE, MHH, HZI) A call for help from the infected brain
18:30‐18:40 Poster awards (chairs: Felix Felmy, Zoology, TiHo + Maximilian Lenz, Neuroanatomy, MHH)
18:40‐18:45 Closing remarks (ZSN board members)
18:45‐ Get together, drinks and pretzels
Poster presentations:
- Henrike Höfs (Neurology, MHH; IMMM, HMTMH), Movement Observation and Imagination in Musician’s Dystonia: preliminary analyses
- Hannah Losch (IMMM HMTMH) Brain Activation in Short‐Term Musical Learning
- Marie Claire Ottinger (Pharmacology, TiHo), Effects of the potassium channel opener azetukalner on seizure thresholds in rats
- Ashraqat Ahmed (INI, Hannover), Identification of mechanosensitive Ca²⁺ channels in Cerebral Cavernous Malformations pathogenesis
- Kurt‐Wolfram Sühs (Neurology, MHH) Anti‐DAGLA autoantibodies detected in CSF represent novel biomarkers for rapidly progressive cerebellitis
- Candra Ohsmer (Zoology, TiHo), Imaging of energy consumption reveals evolutionary robustness despite biophysical differences in neurons of the medial nucleus of the trapezoid body
- Kathrin Lämmerhirt (Toxicology, TiHo) Chronic Pain in a Dish: Towards Human‐Relevant Models of Neuron‐Mediated Chronic Pain
- Laura Console‐Meyer, (Zoology TiHo) Species‐dependent adaptation of input‐output function in the medial nucleus of the trapezoid body
- Isabell Drath (Pharmacology, TiHo) Nanoparticle‐based nose‐to‐brain delivery of small RNA to reduce alpha‐synuclein pathology in a mouse model of Parkinson’s disease (Thy1‐aSyn)
- Malte Feja (Pharmacology, TiHo) Thy1‐aSyn mice as a translational model for developing alpha‐ synuclein‐targeted therapies in synucleinopathies
- Daniela Zalpanow (Pharmacology, TiHo) Characterization of neuroprotective effects mediated by prolyl endopeptidase‐inhibitory compounds for the treatment of Parkinson’s disease
- Joachim Runge (Neurosurgery, MHH) Are Men More Likely to Undergo Functional Stereotactic Neurosurgery? A Comparative Study
- Charlotte Schob (Neuroanatomy, MHH) P301L‐tau expression in the entorhinal cortex leads to increased excitatory neurotransmission in hippocampal granule cells
- Jannik Schwabe, (Clinical Biochemistry, MHH) Polysialic acid (polySia) in immune regulation of the tumor microenvironment
- Lina Gretenkort (Clinical Biochemistry, MHH) Phenotypic characterization and single cell transcriptomic analysis of cortical microglia in aging St8sia4‐/‐ mice
- Melissa Grabinski (Zoology, TiHo; LUH) Developmental alterations of membrane propertiesin PnC giant neurons
- Arif Abdulbaki (Neurosurgery, MHH) Deep brain stimulation (DBS) as effective therapy for obsessive‐ compulsive disorder (OCD) and its associated co‐morbidities
- Pauline Kaltenbach (IMMM, HMTMH) Predicting the Altered Prefrontal Positivity of Pain Evoked Potentials in Musicians by Anxiety
- Akiho Suzuki (IMMM, HMTMH) Pain Neuroscience Education for Musicians
- Hauke Siewertsen (IMMM, HMTMH) Dynamics of Attentional Focus in Musical Performance: Psychophysiological and Subjective Correlates of Stress
- Cody Adams‐Niedergeses (Toxicology, TiHo) PeriMyelinTox: A Stem Cell Based Approach to Assessing Adult Peripheral Myelin Toxicity
- Mesbah Alam (Neurosurgery, MHH) Nonlinear analytic approaches (FD analysis), to characterize network activity in PD
- Franziska Decker (Neurosurgery, MHH) Early‐life lesions of the fastigial nucleus in rats affect cognitive performance and neural information processing in the medial prefrontal cortex (mPFC) in adulthood
- Julian Ghani (IMMM, HMTMH) Alterations in Resting State Connectivity in Task‐Specific Tremor in Musicians
- Bassam G. Haddad (Neurophysiologie, MHH) The molecular basis of voltage‐driven sound amplification in the inner ear
- Bassam G. Haddad (Neurophysiology, MHH) Molecular mechanisms underlying ionic conduction and rectification in Cx46 and Cx50 gap junctions
- Nikolaos Kladisios (Zoology, TiHo) Characterization of sound evoked responses in neurons of the INLL
- Kathrin D. Wicke (Zoology, TiHo) Functional organization principle in the INLL to integrate sound frequencies
- Amrah Gasimli (IMMM, HMTMH) Augmented pain perception in musicians due to neuroplasticity‐ induced alterations
- Vitali Wert (Psychiatry, MHH) Interactomics of disease‐relevant proteins to characterize pathomechanisms
- Miriam Rebekka Rühling (Pediatrics, MHH) Towards simplification of ketogenic diet: Impact of ß‐ hydoxybutyrate, medium chain fatty acids C8 and C10 on sirtuin function and mitochondrial Respiratory Chain
- Miriam Rebekka Rühling (Pediatrics, MHH) Impact of Ketogenic diet on Sirtuins in Children with pharmaco‐resistant Epilepsy in vivo
- Kristina Lau (Pharmacology, TiHo) Primary microglia isolated from adult Thy1‐aSyn mice represent a valuable tool to study inflammation
- Sonali Valvaikar, (Neurology, MHH) Impact of gut associated, microbial metabolites on metabolic function and neuronal activity of hiPSCs‐derived dopaminergic neurons in context of Parkinson’s disease
- Rebecca Kotzur (Pharmacology, TiHo) Hypoxia as potential regulator of inflammation in Parkinson’s disease
- Andreas Pavlou (TWINCORE, MHH, HZI) Mitochondrial antiviral‐signaling (MAVS) in brain‐resident myeloid cells is essential for antigen cross‐presentation and the relicensing of protective, infiltrating CD8+ T cells
- Beate Sodeik (Virology, MHH) Herpes Simplex Virus enters the nervous system after local infection of keratinocytes and cutaneous Schwann cells in murine and human skin explants
- Calderon Hampel, Noemi (Neuroanatomy, MHH) Organotypic tissue cultures are a platform to investigate cytomegalovirus infection of the central nervous system.
- Christopher Käufer (Pharmacology, TiHo) SARS‐CoV‐2 Spike S1 Protein: a Direct Neuroinflammatory Trigger Exacerbating Parkinson's Disease‐related Pathology in Mice
- Rongrong Guo (Virology, MHH) The role of the neuronal intrinsic and innate immune response during herpes simplex virus infection
- Laura Schaltz (Biochemistry, TiHo) Characterisation of viable and suicidal NETs in a model of the blood‐ cerebrospinal fluid barrier during Streptococcus suis infection
- Tobias Hegelmaier (Neurology, MHH) Anti‐CD19 CAR‐T therapy, a transformative approach for treatment‐refractory neuroimmunological diseases
- Jeanne de la Roche (Neurophysiology, MHH) Functional characterization of a FEPS‐related TRPA1 channel mutation L830P
- Tina Davis (IMMM, HMTMH) Small keys, big changes – adaptation of piano students to ergonomically scaled piano keyboards
- Ben Fishman (Psychiatry, MHH) Investigations of the Longitudinal Epigenetics of Polytrauma Injuries in a Human Cohort Study
- Jakob Wenner (Psychiatry, MHH) In silico analysis of BDNF methylation data in the context of depression
- Maria Antonia Joseph (Pharmacology, TiHo) Does Spinal Muscular Atrophy (SMA) lead to alterations of molecular networks in the brain?
- Maira Lieneke (Pharmacology, TiHo) Effects of the MAGL inhibitor MJN110 on acute seizure thresholds in rats
- Jan‐Philipp Machtens (Neurophysiologie, MHH) Calcium‐activated chloride channel TMEM16A opens via pi‐helical transition in transmembrane segment 4
- Ramona Schuppner (Neurology, MHH) Thrombus‐based inflammatory gene expression profilesidentify etiology of cerebral large vessel occlusion
- Julya Hempel (Pediatrics, MHH) Immune‐mediated necrotizing myopathy with positive HMG‐CoA reductase antibodies: Diagnostic challenges and therapeutic options.
- Sebastian Meller (Neurology, TiHo) Medium‐Chain Triglyceride Supplementation Elicits Neurochemical Antiseizure Signals in the Healthy Canine Brain
- Friederike Twele (Neurology, TiHo) Impact of rTMS Treatment Duration on Seizure Control in Dogs with Drug‐Resistant Idiopathic Epilepsy
- Holger Volk (Neurology, TiHo) Characterization of feline and canine dementia to discover disease‐ modifying therapies for human and animal patients
- Diana Voitsekhovych (Pharmacology, TiHo), Investigations on proteinopathies along the gut‐brain axis in dogs
- Hannah Maier (Psychiatry, MHH) P4D ‐ Personalized, Predictive, Precise, and Preventive Medicine for Depression, a multicenter cohort study
- Lan Ye (Neurology, MHH) Metabolomisches CSF‐Profil atypischer Parkinson‐Syndrome: Biomarker zur Differentialdiagnose
- Kirsten Jahn (Psychiatry, MHH) Extended epigenetic investigation of the androgen system‐related genes AR and CYP19A1 (aromatase) in child sexual offending and pedophilia
- Rico Haas (Psychiatry, MHH) Neural processing of social scenes in men who offend or are at risk: evidence from a multimodal study of neurobiological and psychological correlates of sexualised violence against women
- Andre Zeug (Neurophysiology, MHH) From Structure to Function: Multi‐Scale Quantitative Imaging of Brain Plasticity
- Franziska Müller (Neurophysiology, MHH) Custom‐tailored imaging approaches enable a comprehensive dissection of astrocyte interactions with other brain cells
- Pia Kruse (Neuroanatomy, MHH) State‐dependent effects of all‐trans retinoic acid on hippocampal CA1 pyramidal neurons
- Laurin Gründker (Neuroanatomy, MHH) Viral infection induces alterations in synaptic transmission in the hippocampus
- Sandra Weiß (Pharmakologie, TiHo) Nanoparticle-mediated RNA interference to regulate alpha-synuclein expression in an in vitro Parkinson‘s disease model
- Sanaa Abdelmalek Mahmoud (Biochemistry, TiHo) Misrouted NPC1 Protein Drives Cholesterol Overload in Niemann-Pick C
