Symposium Program Overview 2-7 pm

13:00‐14:00 Registration (hang up posters, copy talks on dedicated speakers PC)

14:00‐14:05 Opening (Franziska Richter Assencio, speaker ZSN board) 

14:05‐14:20 Welcome notes by University Presidents (chair: Joachim Krauss, Neurosurgery, MHH)

  • 14:05‐14:10 Prof. Dr. Denise Hilfiker‐Kleiner (MHH)
  • 14:10‐14:15 Prof. Dr. Klaus Osterrieder (TiHo)
  • 14:15‐14:20 Prof. Dr. Hans Jürgen Prömel (HMTMH)

14:20‐ 14:50   Kick‐off talks (chair: Joachim Krauss, Neurosurgery, MHH)

  • 14:20‐14:30 Aiden Haghikia (Neurology, MHH) 
  • 14:30‐14:40 Franziska Richter Assencio (Pharmacology, TiHo) 
  • 14:40‐14:50 Florian Worschech (IMMM, HMTMH)

14:50‐16:10 Short talks of ZSN members I (chair: Maximilian Lenz, Neuroanatomy, MHH)

  1. Kerstin Schwabe (Neurosurgery, MHH) Translational aspects of cognitive behavior and neural processing of sensory information using the three‐class oddball paradigm 
  2. Amelie Eichler (Neuroanatomy, MHH) Functional tissue screening reveals synaptic dysfunction in anti‐ DAGLA autoimmune encephalitis 
  3. Bettina Seeger (Toxicology, TiHo) Modeling Infection‐Induced Neurodevelopmental Disorders in a Human Stem Cell–Based Brain Model 
  4. Nadine Brückner (Virology, MHH) Repression and maintenance of Varicella‐zoster virus genomes during quiescent infection
  5. Johanna Ernst (Neurology, MHH) Biomarker‐Based Identification of Cardioembolic Stroke using Symmetric Dimethylarginine
  6. Sebastian Meller (Neurology, TiHo) Neuromodulation of the Olfactory System against Epilepsy: Mapping and Decoding Olfactory Pharmacology to Combat Neurological Diseases
  7. Hauke Thiesler (Clinical Biochemistry, MHH) Intranasal application of polysialic acid fragments of specific size alleviate synaptic and cognitive symptoms in mouse models of dementia 
  8. Maren von Köckritz‐Blickwede (Biochemistry, TiHo) Oxygen‐Dependent Modulation of Neutrophil Responses in Bacterial Meningitis 
  9. Evgeni Ponimaskin (Neurophysiology, MHH) Molecular microscopy for understanding neuronal function and dysfunction 
  10. Frank Brand (Human genetics, MHH) Germline variants in ATM, BRCA2, other cancer predisposition and novel candidate genes are implicated in glioma risk in adult glioma patients with a familial or personal history of tumors

16:10‐17:00 Group photo in the lecture hall, followed by poster session with coffee break 

17:00‐18:30 Short talks of ZSN members II (chair: Andreas Beineke, Pathology, TiHo)

    11. Peter Claus (Psychiatry, MHH) The neurodevelopmental and neurodegenerative disease Spinal Muscular Atrophy (SMA) as a              paradigm for causal analyses of pathomechanisms
    12. Jan‐Philipp Machtens (Neurophysiology, MHH) Glutamate transport at atomic resolution
    13. Silja Hein (Physiology, TiHo) Effects of feacal supernatants from human irritable bowel syndrom patients on enteric and                        dorsal root ganglia neurons
    14. Fabian Sternkopf  (IMMM, HMTMH) Musicians' Pain: Altered Pain Processing in Musicians
    15. Ingo Gerhauser (Pathology, TiHo) Enzyme inhibition as treatment strategy in GM1 gangliosidosis 
    16. Tillmann Krüger (Psychiatry, MHH) Persistent genital arousal disorder/genitopelvic dysesthesia (PGAD/GPD): Investigation of            clinical features and brain activity at rest (rsfMRI) in a rare and unknown disease 
    17. Lisa Maria Haiber (Toxicology, TiHo) Establishing Chemical Labeling of Cell‐Surface Glycans in 3D Human Neurospheres to                Study Physiological and Stress‐Induced Remodeling 
    18. Meike Dirks (Neurology, MHH) ACCESS – Outreach medical care for housebound patients with Post‐ COVID syndrome or ME/            CFS of any cause 
    19. Herbert Hildebrandt (Clinical Biochemistry, MHH) PolySia‐Siglec interactions as novel innate immune checkpoints in                              glioblastoma, myelin repair and aging 
    20. Hanna Felicitas Klein (IMMM, HMTMH) Temporal prediction and accuracy in pianists with task‐ specific dystonia 
    21. Ulrich Kalinke (TWINCORE, MHH, HZI) A call for help from the infected brain

18:30‐18:40   Poster awards (chairs: Felix Felmy, Zoology, TiHo + Maximilian Lenz, Neuroanatomy, MHH)

18:40‐18:45   Closing remarks (ZSN board members)

18:45‐             Get together, drinks and pretzels

Poster presentations:

  1. Henrike Höfs (Neurology, MHH; IMMM, HMTMH), Movement Observation and Imagination in Musician’s Dystonia: preliminary analyses 
  2. Hannah Losch (IMMM HMTMH) Brain Activation in Short‐Term Musical Learning 
  3. Marie Claire Ottinger (Pharmacology, TiHo), Effects of the potassium channel opener azetukalner on seizure thresholds in rats 
  4. Ashraqat Ahmed (INI, Hannover), Identification of mechanosensitive Ca²⁺  channels in Cerebral Cavernous Malformations pathogenesis 
  5. Kurt‐Wolfram Sühs (Neurology, MHH) Anti‐DAGLA autoantibodies detected in CSF represent novel biomarkers for rapidly progressive cerebellitis 
  6. Candra Ohsmer (Zoology, TiHo), Imaging of energy consumption reveals evolutionary robustness despite biophysical differences in neurons of the medial nucleus of the trapezoid body 
  7. Kathrin Lämmerhirt (Toxicology, TiHo) Chronic Pain in a Dish: Towards Human‐Relevant Models of Neuron‐Mediated Chronic Pain 
  8. Laura Console‐Meyer, (Zoology TiHo) Species‐dependent adaptation of input‐output function in the medial nucleus of the trapezoid body 
  9. Isabell Drath (Pharmacology, TiHo) Nanoparticle‐based nose‐to‐brain delivery of small RNA to reduce alpha‐synuclein pathology in a mouse model of Parkinson’s disease (Thy1‐aSyn) 
  10. Malte Feja (Pharmacology, TiHo) Thy1‐aSyn mice as a translational model for developing alpha‐ synuclein‐targeted therapies in synucleinopathies 
  11. Daniela Zalpanow (Pharmacology, TiHo) Characterization of neuroprotective effects mediated by prolyl endopeptidase‐inhibitory compounds for the treatment of Parkinson’s disease 
  12. Joachim Runge (Neurosurgery, MHH) Are Men More Likely to Undergo Functional Stereotactic Neurosurgery? A Comparative Study 
  13. Charlotte Schob (Neuroanatomy, MHH) P301L‐tau expression in the entorhinal cortex leads to increased excitatory neurotransmission in hippocampal granule cells 
  14. Jannik Schwabe, (Clinical Biochemistry, MHH) Polysialic acid (polySia) in immune regulation of the tumor microenvironment 
  15. Lina Gretenkort (Clinical Biochemistry, MHH) Phenotypic characterization and single cell transcriptomic analysis of cortical microglia in aging St8sia4‐/‐ mice 
  16. Melissa Grabinski (Zoology, TiHo; LUH) Developmental alterations of membrane propertiesin PnC giant neurons 
  17. Arif Abdulbaki (Neurosurgery, MHH) Deep brain stimulation (DBS) as effective therapy for obsessive‐ compulsive disorder (OCD) and its associated co‐morbidities 
  18. Pauline Kaltenbach (IMMM, HMTMH) Predicting the Altered Prefrontal Positivity of Pain Evoked Potentials in Musicians by Anxiety 
  19. Akiho Suzuki (IMMM, HMTMH) Pain Neuroscience Education for Musicians 
  20. Hauke Siewertsen (IMMM, HMTMH) Dynamics of Attentional Focus in Musical Performance: Psychophysiological and Subjective Correlates of Stress 
  21. Cody Adams‐Niedergeses (Toxicology, TiHo) PeriMyelinTox: A Stem Cell Based Approach to Assessing Adult Peripheral Myelin Toxicity     
  22. Mesbah Alam (Neurosurgery, MHH) Nonlinear analytic approaches (FD analysis), to characterize network activity in PD 
  23. Franziska Decker (Neurosurgery, MHH) Early‐life lesions of the fastigial nucleus in rats affect cognitive performance and neural information processing in the medial prefrontal cortex (mPFC) in adulthood 
  24. Julian Ghani (IMMM, HMTMH) Alterations in Resting State Connectivity in Task‐Specific Tremor in Musicians
  25. Bassam G. Haddad (Neurophysiologie, MHH) The molecular basis of voltage‐driven sound amplification in the inner ear 
  26. Bassam G. Haddad (Neurophysiology, MHH) Molecular mechanisms underlying ionic conduction and rectification in Cx46 and Cx50 gap junctions 
  27. Nikolaos Kladisios (Zoology, TiHo) Characterization of sound evoked responses in neurons of the INLL 
  28. Kathrin D. Wicke (Zoology, TiHo) Functional organization principle in the INLL to integrate sound frequencies 
  29. Amrah Gasimli (IMMM, HMTMH) Augmented pain perception in musicians due to neuroplasticity‐ induced alterations 
  30. Vitali Wert (Psychiatry, MHH) Interactomics of disease‐relevant proteins to characterize pathomechanisms 
  31. Miriam Rebekka Rühling (Pediatrics, MHH) Towards simplification of ketogenic diet: Impact of ß‐ hydoxybutyrate, medium chain fatty acids C8 and C10 on sirtuin function and mitochondrial Respiratory Chain 
  32. Miriam Rebekka Rühling (Pediatrics, MHH) Impact of Ketogenic diet on Sirtuins in Children with pharmaco‐resistant Epilepsy in vivo 
  33. Kristina Lau (Pharmacology, TiHo) Primary microglia isolated from adult Thy1‐aSyn mice represent a valuable tool to study inflammation 
  34. Sonali Valvaikar, (Neurology, MHH) Impact of gut associated, microbial metabolites on metabolic function and neuronal activity of hiPSCs‐derived dopaminergic neurons in context of Parkinson’s disease 
  35. Rebecca Kotzur (Pharmacology, TiHo) Hypoxia as potential regulator of inflammation in Parkinson’s disease 
  36. Andreas Pavlou (TWINCORE, MHH, HZI) Mitochondrial antiviral‐signaling (MAVS) in brain‐resident myeloid cells is essential for antigen cross‐presentation and the relicensing of protective, infiltrating CD8+ T cells 
  37. Beate Sodeik (Virology, MHH) Herpes Simplex Virus enters the nervous system after local infection of keratinocytes and cutaneous Schwann cells in murine and human skin explants 
  38. Calderon Hampel, Noemi (Neuroanatomy, MHH) Organotypic tissue cultures are a platform to investigate cytomegalovirus infection of the central nervous system. 
  39. Christopher Käufer (Pharmacology, TiHo) SARS‐CoV‐2 Spike S1 Protein: a Direct Neuroinflammatory Trigger Exacerbating Parkinson's Disease‐related Pathology in Mice 
  40. Rongrong Guo (Virology, MHH) The role of the neuronal intrinsic and innate immune response during herpes simplex virus infection   
  41. Laura Schaltz (Biochemistry, TiHo) Characterisation of viable and suicidal NETs in a model of the blood‐ cerebrospinal fluid barrier during Streptococcus suis infection 
  42. Tobias Hegelmaier (Neurology, MHH) Anti‐CD19 CAR‐T therapy, a transformative approach for treatment‐refractory neuroimmunological diseases 
  43. Jeanne de la Roche (Neurophysiology, MHH) Functional characterization of a FEPS‐related TRPA1 channel mutation L830P 
  44. Tina Davis (IMMM, HMTMH) Small keys, big changes – adaptation of piano students to ergonomically scaled piano keyboards 
  45. Ben Fishman (Psychiatry, MHH) Investigations of the Longitudinal Epigenetics of Polytrauma Injuries in a Human Cohort Study 
  46. Jakob Wenner (Psychiatry, MHH) In silico analysis of BDNF methylation data in the context of depression 
  47. Maria Antonia Joseph (Pharmacology, TiHo) Does Spinal Muscular Atrophy (SMA) lead to alterations of molecular networks in the brain?
  48. Maira Lieneke (Pharmacology, TiHo) Effects of the MAGL inhibitor MJN110 on acute seizure thresholds in rats 
  49. Jan‐Philipp Machtens (Neurophysiologie, MHH) Calcium‐activated chloride channel TMEM16A opens via pi‐helical transition in transmembrane segment 4 
  50. Ramona Schuppner (Neurology, MHH) Thrombus‐based inflammatory gene expression profilesidentify etiology of cerebral large vessel occlusion 
  51. Julya Hempel (Pediatrics, MHH) Immune‐mediated necrotizing myopathy with positive HMG‐CoA reductase antibodies: Diagnostic challenges and therapeutic options.   
  52. Sebastian Meller (Neurology, TiHo) Medium‐Chain Triglyceride Supplementation Elicits Neurochemical Antiseizure Signals in the Healthy Canine Brain 
  53. Friederike Twele (Neurology, TiHo) Impact of rTMS Treatment Duration on Seizure Control in Dogs with Drug‐Resistant Idiopathic Epilepsy 
  54. Holger Volk (Neurology, TiHo) Characterization of feline and canine dementia to discover disease‐ modifying therapies for human and animal patients 
  55. Diana Voitsekhovych (Pharmacology, TiHo), Investigations on proteinopathies along the gut‐brain axis in dogs 
  56. Hannah Maier (Psychiatry, MHH) P4D ‐ Personalized, Predictive, Precise, and Preventive Medicine for Depression, a multicenter cohort study 
  57. Lan Ye (Neurology, MHH) Metabolomisches CSF‐Profil atypischer Parkinson‐Syndrome: Biomarker zur Differentialdiagnose 
  58. Kirsten Jahn (Psychiatry, MHH) Extended epigenetic investigation of the androgen system‐related genes AR and CYP19A1 (aromatase) in child sexual offending and pedophilia 
  59. Rico Haas (Psychiatry, MHH) Neural processing of social scenes in men who offend or are at risk: evidence from a multimodal study of neurobiological and psychological correlates of sexualised violence against women 
  60. Andre Zeug (Neurophysiology, MHH) From Structure to Function: Multi‐Scale Quantitative Imaging of Brain Plasticity 
  61. Franziska Müller (Neurophysiology, MHH) Custom‐tailored imaging approaches enable a comprehensive dissection of astrocyte interactions with other brain cells 
  62. Pia Kruse (Neuroanatomy, MHH) State‐dependent effects of all‐trans retinoic acid on hippocampal CA1 pyramidal neurons
  63. Laurin Gründker (Neuroanatomy, MHH) Viral infection induces alterations in synaptic transmission in the hippocampus
  64. Sandra Weiß (Pharmakologie, TiHo) Nanoparticle-mediated RNA interference to regulate alpha-synuclein expression in an in vitro Parkinson‘s disease model
  65. Sanaa Abdelmalek Mahmoud (Biochemistry, TiHo) Misrouted NPC1 Protein Drives Cholesterol Overload in Niemann-Pick C

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